Clinical and Experimental Otorhinolaryngology

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Review

2026;19(1)

Nrf2: A Promising Therapeutic Target for Glucocorticoid-Resistant Chronic Rhinosinusitis

Yue Wang, Yi Yang

Clin Exp Otorhinolaryngol. 2026;19(1):21-34.

Chronic rhinosinusitis (CRS) presents a challenge for otolaryngologists due to its complex management and high recurrence rates. Glucocorticoids (GCs) are widely employed for their potent anti-inflammatory effects across various inflammatory...

Review

2026;19(1)

The Role of Innate T Cells in Inflammatory Disorders in Asthma and Chronic Rhinosinusitis

Myeong-seok Lee, Dae Woo Kim, You Jeong Lee

Clin Exp Otorhinolaryngol. 2026;19(1):35-44.

Chronic rhinosinusitis (CRS) and asthma frequently coexist and represent heterogeneous inflammatory disorders of the upper and lower airways, respectively. Type 2 inflammation, mediated by eosinophils and CD4 T cells, has...

Review

2026;19(1)

Prognostic Utility of the Albumin-to-Alkaline Phosphatase Ratio in Head and Neck Cancer: A Systematic Review and Meta-Analysis

Yun-Ting Wang, Adarsh Kudva, Yen-Ting Lu, Liang-Tseng Kuo, Chia-Hsuan Lai, Yuan-Hsiung Tsai, Chun-Ta Liao, Ku-Hao Fang, Chung-Jan Kang, Ethan I. Huang, et al.

Clin Exp Otorhinolaryngol. 2026;19(1):45-54.

Objectives. The prognostic value of the pretreatment albumin-to-alkaline phosphatase ratio (AAPR) in head and neck cancer (HNC) remains uncertain. This meta-analysis aimed to evaluate the predictive role of AAPR for...

Original Article

2026;19(1)

Activation of the Gamma-Aminobutyric Acid (GABA)ergic Neural Circuit in Salicylate-Induced Tinnitus: the Inferior Colliculus to the Medial Geniculate Body

Xu-Yuan Peng, Jiang Wang, Ming-Yue Gong, Li-Yuan Zhang, Min Zhang, Zhi-Bin Chen, Zheng-Quan Tang, Lei Cheng

Clin Exp Otorhinolaryngol. 2026;19(1):55-69.

Objectives. This study aimed to investigate the regulatory functions of gamma-aminobutyric acid (GABA)ergic neural circuits from the inferior colliculus (IC) to the medial geniculate body (MGB) in salicylate-induced tinnitus. Methods. Mice...

Original Article

2026;19(1)

Efficacy and Safety of Fat Graft Myringoplasty Combined With Platelet-Rich Plasma for Managing Chronic Tympanic Membrane Perforations: A Systematic Review and Meta-Analysis

Yun Jin Kang, Gulnaz Stybayeva, Se Hwan Hwang

Clin Exp Otorhinolaryngol. 2026;19(1):70-78.

Objectives: Platelet-rich plasma (PRP) is an autologous product derived from whole blood through the process of gradient density centrifugation. Autologous PRP has been shown to be safe and effective in...

Original Article

2026;19(1)

Treatment Outcomes of the Inferior Meatus Augmentation Procedure With Autologous Costal Cartilage for Empty Nose Syndrome

Jang Wook Gwak, Yong Ju Jang

Clin Exp Otorhinolaryngol. 2026;19(1):79-85.

Objectives. Empty nose syndrome (ENS) is a rare postoperative complication that can develop following turbinate surgery. Here, we present our clinical experience and a comprehensive analysis of the inferior meatus...

Original Article

2026;19(1)

Synergistic Exacerbation of Allergic Inflammation by Combined Exposure to Air-Pollutants in a Murine Model of Allergic Rhinitis

Joo-Hoo Park, Jee Won Moon, Yeong-In Jo, Hwa Eun Yang, Subin Cho, Hyeongguk Son, Hyun-Woo Yang, Dae Jin Song, Il-Ho Park

Clin Exp Otorhinolaryngol. 2026;19(1):86-96.

Objectives Allergic rhinitis (AR) is a chronic inflammation of the nasal mucosa triggered by environmental allergens. Although its pathophysiology has been extensively investigated, the influence of environmental aggravating factors—particularly combined pollutant...

Original Article

2026;19(1)

Posterior Pillar Hypertrophy as a Novel Anatomical Predictor of Surgical Success in Obstructive Sleep Apnea

Yeonsu Jeong, Jeong Jin Park, Min-Seok Rha, Hyung-Ju Cho

Clin Exp Otorhinolaryngol. 2026;19(1):97-102.

Objectives Sleep apnea surgery is effective only in appropriately selected patients, making accurate identification of candidates essential. This study aimed to introduce a novel anatomical index for identifying patients most likely...

Journal Metrics

5.6 CiteScore

3.4 Journal Impact Factor

14.9% Acceptance Rate

13.6 days Submission to First
Decision

Current Issue: Volume 19(1); Feb 2026

Harnessing Machine Learning for Personalized Care of Patients With Idiopathic Sudden Sensorineural Hearing Loss: A Multicenter Cohort Study Yen-Ting Guo, Ching-Ting Tan, Chen-Chi Wu, Chun-Ying Wang, Chein-Yu Huang, Tzu-Hsiang Yang, Ting-Yi Lee, Ting-Hua Yang, Tien-Chen Liu, Pey-Yu Chen, et al. Original Article PDF	Even Unmanipulated Eyebrows Are Unreliable Landmarks for Evaluating Deviated Noses in Rhinoplasty Su Jin Kim, Kun Hee Lee, Hong Ryul Jin Original Article Full text PubReader ePub PDF
Subjective and Objective Assessments of Olfactory Function in Patients Taking Anti-obesity Medications Hye Jun Lee, Il-Youp Kwak, Hyun Jin Min Brief Communication Full text PubReader ePub PDF Supplementary Material	Efficacy of Montelukast–Antihistamine Combination Therapy Versus Antihistamine Monotherapy in Allergic Rhinitis: A Systematic Review and Meta-Analysis Ji-Sun Kim, Gulnaz Stybayeva, Se Hwan Hwang Original Article Cited By 1 PDF

Journal Impact Factor 3.4

The Role of Innate T Cells in Inflammatory Disorders in Asthma and Chronic Rhinosinusitis Clin Exp Otorhinolaryngol. 2026;19(1):35-44.

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