We have reviewed all theories that explain the pathogenesis of acquired cholesteatoma.
Different mechanisms for bone resorption in that disease were also described in details.
No single theory is enough to explain all events in acquired cholesteatoma.
Experimental research should go on to provide better understanding and non-surgical therapy.
Ototoxicity is one of the main side effect which restrict the use of Gentamicin.
Garlic with its intrinsic antioxidant activity may beneficial in prevention from ototoxicity.
Garlic derivatives (S-allylmercaptocysteine [SAMC], diallyl disulfide [DD], and S-allylcysteine [SAC]) seems to attenuate gentamicin-induced hearing loss.
The effect of SAMC and DD seems to be more prominent than that of SAC.
Seven hundred seventy six and 233 participants in the groups diagnosed without and with osteoporosis (OP) were examined hearing results.
In the total cohort, the proportion of participants with hearing loss in the group without and with OP was 20.4% and 30.9%, respectively (P=0.001).
In the propensity score matched (PSM) cohort, adjusted model for risk factor, no significant associations among lumbar spine or femoral neck T-scores and changes in the hearing
This study did not demonstrate the association between bone mineral density and hearing impairment in the study population of postmenopausal Korean women.
Risk factors of visual disturbance were investigated in 47 patients with sphenoid sinus fungal ball.
Visual disturbance occurred in 18 of 47 (17%) patients.
Old aged, diabetic, and CT-sphenoid bony defect-containing patients were more likely to have visual disturbance.
However, the risk factors were not confirmed by the multivariate analyses.
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